Proteomics
Recent findings from National Institutes of Health highlight research in proteomics
Published in Drug Week, January 12th, 2007
New research, "A three-dimensional model of human organic anion transporter 1: aromatic amino acids required for substrate transport," is the subject of a report. "Organic anion transporters (OATs) play a critical role in the handling of endogenous and exogenous organic anions by excretory and barrier tissues. Little is known about the OAT three-dimensional structure or substrate/protein interactions involved in transport," researchers in the United States report.
"In this investigation, a theoretical three-dimensional model was generated for human OAT1 (hOAT1) based on fold recognition to the crystal structure of the glycerol 3-phosphate transporter (GlpT) from...
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Source: Drug Week (2007-01-12)
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