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Thrombosis Therapy

Recent studies from School of Medical Sciences add new data to thrombosis therapy

Published in Drug Week, January 19th, 2007

Investigators publish new data in the report "Probucol inhibits in-stent thrombosis and neointimal hyperplasia by promoting re-endothelialization." According to a study from Sydney, Australia, "Evidence suggests that delayed re-endothelialization is responsible for in-stent thrombosis. Probucol inhibits neointimal thickening in animals via enhanced re-endothelialization and is the only oral drug that consistently inhibits restenosis after coronary angioplasty in humans."

"Here, we examined the effects of probucol on re-endothelialization and neointimal formation in a stent model. New Zealand White rabbits were fed a hypercholesterolemic diet with probucol (1%) or...

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