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Breast Cancer

National Cancer Research Institute researcher presents way to predict response to anthracyclines

Published in Drug Week, January 19th, 2007

The anthracycline drugs used as a standard component of chemotherapy for breast cancer patients (doxorubicin and epirubicin) may cause serious side effects, including heart damage.

Women sometimes discontinue therapy, or avoid it altogether, because of anxiety about the effects of these drugs. Unfortunately, some patients will not respond to the drug, and will experience the often-devastating side effects in vain. Now a report from the 29th Annual San Antonio Breast Cancer Symposium suggests that there may be a straightforward way to predict who will respond to anthracycline drugs, based on a commonly measured tumor marker.

Multiple clinical trials...

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