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Antifungals



Scientists at Tohoku Pharmaceutical University, Department of Microbiology describe research in antifungals



March 2nd, 2007

Data detailed in "Hyphal formation of Candida albicans is inhibited by salivary mucin" have been presented. "When mucin was added to Candida albicans under hyphal growth conditions, the hyphal formation was inhibited. After the 24 h incubation, the ratio of hyphal cells was 95.7±1.13% in the absence of mucin and no hyphal cells were observed in the presence of 1000 microg/ml mucin," scientists writing in the journal Biological and Pharmaceutical Bulletin report.

"The ratio of hyphal cells began to decreases at 6 h in the mucin addition group. Although mucin has antifungal activity, the concentration of mucin used in this assay did not inhibit the...


Source: Drug Week (2007-03-02)

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