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Cancer Gene Therapy



Reports summarize cancer gene therapy research from University of Tokyo, Institute of Medical Science



March 2nd, 2007

New research, "Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer," is the subject of a report. In this recent report, researchers in Tokyo, Japan conducted a study "To identify novel biomarkers and therapeutic targets for lung cancers, we screened for genes that were highly transactivated in a large proportion of non-small cell lung cancers (NSCLC) using a cDNA microarray representing 27,648 genes. A gene encoding insulin-like growth factor-II mRNA-binding protein 1 (IMP-1) was selected as a candidate (>or=3-fold expression than in normal lung tissue in about 70% of NSCLCs)."

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Source: Drug Week (2007-03-02)

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