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Allergies Therapy
New findings from Kochi Medical School, Department of Ophthalmology in the area of allergies therapy published
March 2nd, 2007
Scientists discuss in "Differential contributions of B7-1 and B7-2 to the development of murine experimental allergic conjunctivitis" new findings in allergies. "B7-1 and B7-2 are the co-stimulatory molecules that are involved in activation of T cells. We investigated whether B7-1 and B7-2 play a role in the development of T cell-mediated experimental allergic conjunctivitis (EC)," researchers in Japan report. "EC was induced in Balb/c mice by active immunization with ragweed (RW) followed by RW challenge in eye drops. These mice were treated with neutralizing anti-B7-1 Ab, anti-B7-2 Ab, both Abs, anti-cytotoxic T lymphocyte-associated Ag-4 (CTLA-4) Ab or normal IgGs as...
Source: Drug Week (2007-03-02)
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