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Colon Cancer Immunotherapy



Reports on colon cancer immunotherapy findings from Wistar Institute provide new insights



March 2nd, 2007

New investigation results, "Colon carcinoma cells induce CXCL11-dependent migration of CXCR3-expressing cytotoxic T lymphocytes in organotypic culture," are detailed in a study published in Cancer Immunology, Immunotherapy. According to a study from the United States, "Adoptive immunotherapy of cancer patients with cytolytic T lymphocytes (CTL) has been hampered by the inability of the CTL to home into tumors in vivo. Chemokines can attract T lymphocytes to the tumor site, as demonstrated in animal models, but the role of chemokines in T-lymphocyte trafficking toward human tumor cells is relatively unexplored."

"In the present study, the role of chemokines and their...


Source: Drug Week (2007-03-02)

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