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Anti-Infectives
Researchers from Tokyo Women's Medical University, Department of Pharmacy provide details of new studies and findings in the area of anti-infectives
March 2nd, 2007
Scientists discuss in "Sustained release of highly water-soluble drugs with micelle forming ability from polyionic matrix tablets" new findings in anti-infectives. "The aim of present study was to evaluate the application of a hydrophilic matrix tablet capable of polyion complex (PIC-tablet) to a controlled-release device for highly water-soluble drugs. The PIC-tablet was prepared from a mixture of dextran sulfate and [2-(diethylamino)ethyl] dextran chloride, and diltiazem hydrochloride was used as a model drug," scientists in Tokyo, Japan report. "Release tests revealed that the drug release was sustained even in 50% drug loading and was influenced by ionic strength...
Source: Drug Week (2007-03-02)
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