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Antibiotics



Research from King Saud University, Department of Pharmaceutical Chemistry in antibiotics provides new insights



March 2nd, 2007

Scientists discuss in "Enantioanalysis of bisoprolol in human plasma with a macrocyclic antibiotic HPLC chiral column using fluorescence detection and solid phase extraction" new findings in antibiotics. According to a study from Riyadh, Saudi Arabia, "A sensitive, enantioselective, high-performance liquid chromatographic (HPLC) method was developed and validated to determine S-(-)-and R-(+)-bisoprolol in human plasma. Baseline resolution was achieved using the teicoplanin macrocyclic antibiotic chiral stationary phase (CSP) known as Chirobiotic T with a polar ionic mobile phase (PIM) consisting of methanol-glacial acetic acid-triethylamine (100:0.02:0.025, v/v/v) at a flow rate of 1.5...


Source: Drug Week (2007-03-02)

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