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Metabolism

Study Examines Calorie Restriction and Glycemic Load

Published in Drug Week, April 27th, 2007

The first phase of a caloric restriction study in human subjects at the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University found evidence suggesting that calorie-restricted diets differing substantially in glycemic load can result in comparable long-term weight loss.

The study, part of the multi-center Comprehensive Assessment of Long-term Effects of Restricting Intake of Energy (CALERIE) trial, funded by the National Institute on Aging, accounted for dietary factors that affect hunger and satiety, used laboratory techniques to measure adherence, and was the first of its kind to provide a complete set of...

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