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Chemotherapy

Research conducted at School of Dentistry has updated our knowledge about chemotherapy

Published in Drug Week, May 4th, 2007

A report, "Novel synthetic antimicrobial peptides against Streptococcus mutans," is newly published data in Antimicrobial Agents and Chemotherapy. "Streptococcus mutans, a common oral pathogen and the causative agent of dental caries, has persisted and even thrived on the tooth surface despite constant removal and eradication efforts. In this study, we generated a number of synthetic antimicrobial peptides against this bacterium via construction and screening of several structurally diverse peptide libraries where the hydrophobicity and charge within each library was varied incrementally in order to generate a collection of peptides with different biochemical...

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