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Angiogenesis

EntreMed Presents Multi-Mechanism Antitumor Data for ENMD-1420 in Preclinical Models

Published in Drug Week, May 4th, 2007

EntreMed, Inc. (NASDAQ:ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and inflammatory diseases, announced the presentation of results for its preclinical tubulin inhibitor compounds. The data were presented by EntreMed scientists at the American Association for Cancer Research (AACR) Annual Meeting in Los Angeles, California.

Results of the studies presented at the AACR meeting demonstrated a potent, dose-dependent inhibition of tumor growth following the administration of ENMD-1420 (previously CC-5079) in two distinct preclinical models of metastatic lung and colorectal carcinoma. At maximally tolerated doses, tumor...

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