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Study results from Johns Hopkins Medical Institute update understanding of pediatric in children

Published in Drug Week, May 25th, 2007

New research, "Dexmedetomidine for the treatment of postanesthesia shivering in children," is the subject of a report. According to a study from the United States, "Shivering is a common postanesthesia adverse event with multiple etiologies and multiple suggested prophylactic and abortive treatment regimens. Dexmedetomidine, a centrally acting alpha(2)-adrenergic agonist, has been used as a sedative agent and is known to reduce the shivering threshold."

"We hypothesized that children with postanesthesia shivering would reduce shivering behavior following a single bolus dose of dexmedetomidine. Dexmedetomidine was administered in a prospective, open-label fashion. The...

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