Researchers from Kyoto University provide details of new studies and findings in the area of gene therapy

New research, "Efficient gene transduction of neurons by lentivirus with enhanced neuron-specific promoters," is the subject of a report. "In the field of basic and clinical neurosciences, it is important to develop a method for easy delivery and persistent expression of transgene in central neurons. We firstly generated lentiviral vectors with five kinds of neuron-specific promoters, such as synapsin I (SYN), calcium/calmodulin-dependent protein kinase II, tubulin alpha I, neuron-specific enolase and platelet-derived growth factor beta chain promoters and then novel hybrid promoters by fusing cytomegalovirus enhancer (E) to those neuron-specific promoters," investigators in Kyoto, Japan...

Want to see the full article?

• Purchase this article for only $3.00