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Angiogenesis

New angiogenesis study findings reported from Children's Hospital

Published in Drug Week, July 27th, 2007

Fresh data on angiogenesis are presented in the report "Combined therapeutic effects of vinblastine and rapamycin on human neuroblastoma growth, apoptosis, and angiogenesis." According to recent research published in the journal Clinical Cancer Research, "Vinblastine and rapamycin displayed synergistic inhibition of human neuroblastoma-related angiogenesis. Here, we studied the antitumor activity of vinblastine and rapamycin against human neuroblastoma."

"Cell proliferation, cell cycle progression, and apoptosis were evaluated by measuring (3)H-thymidine incorporation, bromodeoxyuridine uptake, and phosphatidylserine exposure, respectively. The in vivo...

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