Clinical Trial Research
Scientists at University of Reading publish new data on clinical trial research
Published in Drug Week, July 27th, 2007
A report, "Covariate heterogeneity in meta-analysis: criteria for deciding between meta-regression and individual patient data," is newly published data in Statistics In Medicine. "Meta-analyses of clinical trials are increasingly seeking to go beyond estimating the effect of a treatment and may also aim to investigate the effect of other covariates and how they alter treatment effectiveness. This requires the estimation of treatment-covariate interactions," researchers in the United Kingdom report.
"Meta-regression can be used to estimate such interactions using published data, but it is known to lack statistical power, and is prone to bias.The use of individual...
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Source: Drug Week (2007-07-27)
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