Published in Drug Week, August 24th, 2007
"To provide a structural basis for understanding the ligand-binding mechanisms of MARCO, we have determined the crystal structure of the mouse MARCO SRCR domain. The recombinant SRCR domain purified as monomeric and dimeric forms, and their structures were determined at 1.78 and 1.77A resolution, respectively. The monomer has a compact globular fold...
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