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Drug Resistance



Frog Plus Frying Pan Equals Better Antibiotic



August 31st, 2007

What do you get when you cross a frog with a frying pan' Possibly a solution to the problem of drug-resistant bugs, research at the University of Michigan suggests.

By creating "Teflon" versions of natural antibiotics found in frog skin, a research team led by biological chemist E. Neil Marsh has made the potential drugs better at thwarting bacterial defenses, an improvement that could enhance their effectiveness. Marsh will discuss the work Aug. 20 at the 234th national meeting of the American Chemical Society in Boston.

Marsh and collaborators work with compounds called antimicrobial peptides (AMPs), which are produced by virtually all animals,...


Source: Drug Week (2007-08-31)

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