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Leishmaniasis Therapy

Studies from University of Tehran, School of Public Health and Institute of Public Health Research in the area of leishmaniasis therapy described

Published in Drug Week, September 21st, 2007

New investigation results, "Comparison of miltefosine and meglumine antimoniate for the treatment of zoonotic cutaneous leishmaniasis (ZCL) by a randomized clinical trial in Iran," are detailed in a study published in Acta Tropica. According to a study from Iran, "This study was a randomized, open label comparison that was designed to determine efficacy and safety of miltefosine as the first oral drug for the treatment of zoonotic cutaneous leishmaniasis caused by Leishmania major in comparison with meglumine antimoniate. Complete clinical response was defined as 100% re-epithelialization of the lesion."

"Definitions of lesion cure and failure were based...

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