Multiple Sclerosis

Chicago Medical Center reports research in multiple sclerosis

Published in Drug Week, September 28th, 2007

According to a study from the United States, "Interferon beta (IFN-beta) therapy reduces relapse rate, MRI lesion development, and delays the progression of disability in relapsing forms of multiple sclerosis. As with other protein therapies, some patients develop neutralizing antibodies (NAbs) that could limit the efficacy of IFN-beta."

"The clinical impact of NAbs is hotly debated. Non-standardized NAb assays, NAb persistence and disappearance, plus a six-month lag before a clinical effect, different IFN-beta species and formulations, variable trial duration, have made interpretation of the significance of NAbs a challenging task. There is a correlation between the...

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Source: Drug Week (2007-09-28)

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