Microbiology
Studies conducted at University Nacional Autonoma of Mexico on microbiology recently published
Published in Drug Week, October 5th, 2007
Data detailed in "Metabolic engineering of Bacillus subtilis for ethanol production: lactate dehydrogenase plays a key role in fermentative metabolism" have been presented. "Wild-type Bacillus subtilis ferments 20 g/liter glucose in 48 h, producing lactate and butanediol, but not ethanol or acetate. To construct an ethanologenic B. subtilis strain, homologous recombination was used to disrupt the native lactate dehydrogenase (LDH) gene (ldh) by chromosomal insertion of the Zymomonas mobilis pyruvate decarboxylase gene (pdc) and alcohol dehydrogenase II gene (adhB) under the control of the ldh native promoter," scientists in Mexico report.
"The values of the...
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Source: Drug Week (2007-10-05)
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