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Cardiovascular Disease Therapy

Data from University of Minnesota provide new insights into cardiovascular disease therapy

Published in Drug Week, November 23rd, 2007

Current study results from the report, 'Sex-specific effects of AGT-6 and ACE I/D on pulse pressure after 6 months on antihypertensive treatment: the GenHAT study,' have been published. "Research suggests pulse pressure (PP) is a predictor of cardiovascular disease, and genes likely influence PP levels. Additionally, gender may be an effect modifier between PP and cardiovascular disease," investigators in the United States report.

"This study addresses whether two renin-angiotensin-aldosterone system (RAAS) variants are associated with PP in a sex-specific manner (genotype-by-sex interaction). Subjects comprised 35,048 GenHAT study participants over 55 years old,...

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