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Antifungals

Beating hospital yeast infection

Published in Drug Week, December 21st, 2007

Increasing numbers of critically ill patients develop fungal or yeast infections, which are associated with high mortality. Now a review published in the online open access journal, Critical Care, compares treatments involving single-drug antifungal prophylaxis (SAP) or a multi-drug regimen of selective digestive tract decontamination (SDD) and suggests that both methods reduce yeast-related morbidity and mortality, but to different extents.

A team from Academic Medical Center Amsterdam, the Netherlands set out to compare the effectiveness of preventative antifungal therapies by trawling the medical databases. This yielded data from more than 5,500 patients enrolled in...

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