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Metabolism

Studies from University of Kerala further understanding of metabolism

Published in Drug Week, December 21st, 2007

"Effect of exogenous selenium at a dose of 10 mu g/kg body weight on the testicular toxicity induced by nicotine in rats was investigated. Male albino rats were maintained for 60 days as follows: (1) control group (normal diet), (2) nicotine group (0.6 mg /kg body weight), (3) selenium (10 mu g/kg body weight), and (4) nicotine (0.6 mg/kg body weight) + selenium (10 mu g/ kg body weight)," investigators in Trivandrum, India report.

"Administration of nicotine caused reduction in sperm count and sperm motility. Activity of HMG CoA reductase and concentration of cholesterol were increased in the testes of the nicotine administered group. Activities of testicular enzymes 3...

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