Drug Resistance

Novel approach strips staph of virulence

Published in Drug Week, February 29th, 2008

An international team of researchers supported by the National Institutes of Health (NIH) has blocked staph infections in mice using a drug previously tested in clinical trials as a cholesterol-lowering agent. The novel approach, described in the February 14 online edition of Science, could offer a new direction for therapies against a bacterium that’s becoming increasingly resistant to antibiotics.

"By following their scientific instinct about a basic biological process, the researchers made a surprising discovery with important clinical implications," said NIH Director Elias A. Zerhouni, M.D. "Although the results are still very preliminary, they offer a promising new...

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Source: Drug Week (2008-02-29)

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