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Gene Chips

Gene chips used to distinguish ventilator-associated pneumonia from underlying critical illness

Published in Drug Week, February 29th, 2008

Critically ill patients who need a ventilator to breathe face a high risk of pneumonia. The lung infection, however, is exceedingly difficult to diagnose because a patient's underlying condition often skews laboratory test results and masks pneumonia's symptoms – a reality that can delay appropriate antibiotic treatment.

Using gene chip technology, scientists at Washington University School of Medicine in St. Louis demonstrate for the first time they can distinguish pneumonia associated with ventilator use from other serious illnesses. The research, published Feb. 13 in the journal Public Library of Science One, suggests that the method may lead to early, more accurate...

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