Life Sciences
Data from Center for Cancer Research provide new insights into life sciences
Published in Drug Week, June 13th, 2008
Researchers detail in 'Cutting edge: rapid accumulation of epidermal CCL27 in skin-draining lymph nodes following topical application of a contact sensitizer recruits CCR10-expressing T cells,' new data in life sciences. "CC chemokine receptor 10 and its ligand, CCL27, are important components of T cell-mediated cutaneous immunity, but whether they influence lymph node (LN) homing by T cells is unknown. In this study, CCL27 protein was detected in skin-draining LN by Western blotting and ELISA although CCL27 mRNA transcripts were low," researchers in the United States report.
"CCL27 protein was present at higher levels in skin-draining LN compared with gut-draining LN...
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Source: Drug Week (2008-06-13)
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