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Proteomics

New proteomics study findings have been reported from Scripps Research Institute, Cell Biology Department

Published in Drug Week, June 13th, 2008

New investigation results, 'Motif-specific sampling of phosphoproteomes,' are detailed in a study published in Journal of Proteome Research. "Phosphoproteomics, the targeted study of a subfraction of the proteome which is modified by phosphorylation, has become an indispensable tool to study cell signaling dynamics. We described a methodology that linked phosphoproteome and proteome analysis based on Ba2+ binding properties of amino acids," researchers in the United States report.

"This technology selected motif-specific phosphopeptides independent of the system under analysis. MudPIT (Multidimensional Identification Technology) identified 1037 precipitated...

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