Imperial College London

Alzheimer's disease patients show improvement in trial of new drug

Published in Drug Week, August 15th, 2008

A new drug has been shown to improve the brain function of people with early stage Alzheimer's disease and reduce a key protein associated with the disease in the spinal fluid, in a small study published in the journal Lancet Neurology and presented at the 2008 Alzheimer's Association International Conference on Alzheimer's Disease.

The drug, known as PBT2, counteracts the production and build-up of a protein called amyloid-beta that occurs in Alzheimer's disease. This protein, which can build up into a 'plaque', is believed to be toxic to brain cells and to prevent them from functioning properly.

Seventy-eight participants with early stage...

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Source: Drug Week (2008-08-15)

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