Physiology

Research in the area of physiology reported from University of Calgary

Published in Drug Week, August 15th, 2008

According to recent research from Calgary, Canada, "The intracellular calcium ion is one of the most important secondary messengers in eukaryotic cells. Ca2+ signals are translated into physiological responses by EF-hand calcium-binding proteins such as calmodulin (CaM)."

"Multiple CaM isoforms occur in plant cells, whereas only a single CaM protein is found in animals. Soybean CaM isoform 1 (sCaM1) shares 90% amino acid sequence identity with animal CaM (aCaM), whereas sCaM4 is only 78% identical. These two sCaM isoforms have distinct target-enzyme activation properties and physiological functions. sCaM4 is highly expressed during the self-defense reaction of the plant...

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Source: Drug Week (2008-08-15)

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