American Academy of Sleep Medicine

Insomnia in women with breast cancer linked to heart rate dysregulation

Published in Drug Week, October 31st, 2008

A study in the October 15 issue of the Journal of Clinical Sleep Medicine shows that respiratory sinus arrhythmia (RSA) is a significant predictor of insomnia in women with breast cancer and confirmed that longer nocturnal wake episodes were associated with a flatter diurnal cortisol slope.

Results of this study confirmed a relationship between frequent awakenings and abnormal cortisol (a steroid hormone that regulates blood pressure), rhythms in metastatic breast cancer, thus concluding that a disrupted cortisol rhythm may have serious medical implications in women with breast cancer.

With the addition of demographics, disease severity and...

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Source: Drug Week (2008-10-31)

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