Arthritis Gene Therapy
Research from Ben-Gurion University, Department of Clinical Biochemistry provides new data about arthritis gene therapy
Published in Drug Week, December 12th, 2008
A new study, 'Reduction of cPLA2alpha overexpression: an efficient anti-inflammatory therapy for collagen-induced arthritis,' is now available. According to a study from Beer Sheva, Israel, "Cytosolic phospholipase A2alpha (cPLA2) plays an important role in the development of several inflammatory diseases. The aim of the present study is to determine whether inhibition of cPLA2 expression, using specific antisense oligonucleotides against cPLA2 (antisense), is efficient in reducing inflammation after its development."
"Two mouse models of inflammation were included in the study: thioglicolate peritonitis and collagen-induced arthritis (CIA). The antisense was found to...
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Source: Drug Week (2008-12-12)
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