Epilepsy

Marinus Pharmaceuticals, Inc. Announces Positive Results of its Phase 2 Clinical Trial of Ganaxolone as Adjunctive Therapy in Adults With Partial Onset Seizures

Published in Drug Week, March 20th, 2009

Marinus Pharmaceuticals, Inc. announced that it met its primary endpoint for its Phase 2 clinical trial investigating the safety and efficacy of ganaxolone as adjunctive therapy in adults with partial onset seizures, a type of epilepsy. In this trial, ganaxolone demonstrated a statistically significant reduction in seizures versus placebo. Efficacy was seen in the first week of dosing. Ganaxolone was also found to be safe and well-tolerated in this population adding to the safety database of more than 950 subjects.

Partial seizures are episodes of abnormal electrical activity in the temporal lobe of the brain, an area near the side of the head, resulting in...

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Source: Drug Week (2009-03-20)

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