Monoclonal Antibodies

Reports from L. Wu and colleagues advance knowledge in monoclonal antibodies

Published in Drug Week, March 20th, 2009

According to a study from San Jose, Costa Rica, "Vogt-Koyanagi-Harada (VKH) syndrome is characterized by bilateral diffuse uveitis associated with auditory, neurological, and cutaneous signs and symptoms. VKH syndrome is a cell-mediated autoimmune disease against melanocytes."

"Choroidal neovascularization (CNV) occurs in 15% of VKH patients and is associated with poor visual prognosis. We report on two patients with VKH syndrome and CNV that were treated with intravitreal bevacizumab. One of the VKH patients also had an extrafoveal CNV membrane and underwent multiple intravitreal injections of bevacizumab in combination with laser photocoagulation, with subsequent...

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Source: Drug Week (2009-03-20)

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