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Myeloma

New findings reported from Mayo Clinic describe advances in myeloma

Published in Drug Week, March 20th, 2009

"The understanding of the pathogenesis of multiple myeloma has undergone a major transformation over the past eight years. New insights into the microenvironment of the plasma cell as well as elucidation of signaling pathways that prevent plasma cell apoptosis are leading to rapid new drug development," scientists writing in the journal Biology of Blood and Marrow Transplantation report.

"The introduction of novel agents has led to a significant increase in survival. Combinations of novel agents are expected to provide higher complete response rate with anticipated prolongation of relapse free and overall survival," wrote M.A. Gertz and colleagues, Mayo...

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