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Study results from I. Goldenberg and colleagues update understanding of life sciences

Published in Drug Week, April 24th, 2009

According to a study from Tel Hashomer, Israel, "Major randomized trials of fibrate therapy demonstrate an inverse relationship between on-treatment high-density lipoprotein cholesterol (HDL-C) increments and clinical outcome. We hypothesized that the degree of HDL-C response to bezafibrate is independently associated with subsequent long-term mortality."

"The risk of death at 16 years of follow-up among 3026 patients with coronary heart disease allocated to the original bezafibrate (n=1509) and placebo (n=1517) arms of the Bezafibrate Infarction Prevention (BIP) trial was related to HDL-C response to bezafibrate therapy, categorized as upper-tertile (> 8 mg/dL) or...

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