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Alcoholism Genetics

Reports from University of Sao Paulo, Department of Gastroenterology add new data to research in alcoholism genetics

Published in Drug Week, April 24th, 2009

A new study, 'CFTR polymorphisms in patients with alcoholic chronic pancreatitis,' is now available. According to recent research from Sao Paulo, Brazil, "Pancreas susceptibility to alcohol is variable and only 5-10% of chronic alcohol abusers develop chronic pancreatitis; the role of genetic factors in this process is unknown. The CFTR gene encodes a protein that acts on epithelial cells and plays a key role in normal exocrine pancreatic function."

"This study investigated the frequency of polymorphisms in intron 8 of the CFTR gene in patients with alcoholic chronic pancreatitis. Three groups of patients were studied: group A -68 adult alcoholics with a diagnosis of...

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