Dementia
Research by W.P. Qin and colleagues in dementia provides new insights
Published in Drug Week, April 24th, 2009
In this recent report published in the journal Archives of Neurology, researchers in the United States conducted a study "To explore mechanisms through which altered peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha) expression may influence Alzheimer disease (AD) amyloid neuropathology and to test the hypothesis that promotion of PGC-1 alpha expression in neurons might be developed as a novel therapeutic strategy in AD. Case-control. Human postmortem brain (hippocampal formation) samples from AD cases and age-matched non-AD cases."
"Using genome-wide complementary DNA microarray analysis, we found that PGC-1 alpha messenger RNA...
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Source: Drug Week (2009-04-24)
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