New investigation results, 'The ataxiaprotein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1,' are detailed in a study published in Human Molecular Genetics. According to recent research published in the journal Human Molecular Genetics, "An extensive protein-protein interaction network has been identified between proteins implicated in inherited ataxias. The protein sacsin, which is mutated in the early-onset neurodegenerative disease autosomal recessive spastic ataxia of Charlevoix-Saguenay, is a node in this interactome."
"Here, we have established the neuronal expression of sacsin and functionally...
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