Therapy

New findings from University of Arizona in the area of therapy published

Published in Drug Week, May 15th, 2009

"Proton pump inhibitor (PPI) failure is very common and may affect up to one-third of the PPI consumers. Identifying the underlying mechanisms for PPI failure in each individual patient is essential for treatment success," scientists writing in the American Journal of Gastroenterology report.

"For residual acid reflux, increasing the PPI dose to twice daily; switching to another PPI, or adding an histamine 2 receptor antagonist could be a successful therapeutic strategy. In patients with duodenogastroesophageal reflux, weak acidic/alkaline reflux and hypersensitivity to acid reflux, therapeutic modalities that reduce transient lower esophageal sphincter...

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Source: Drug Week (2009-05-15)

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