Endometrial Cancer
New data from University of Ljubljana illuminate research in endometrial cancer
Published in Drug Week, May 29th, 2009
"Endometrial cancer is related to estrogen stimulation not opposed by progesterone. We have examined expression of the pre-receptor regulatory enzymes aromatase, 17 beta-hydroxysteroid dehydrogenases (17 beta-HSDs), 20 alpha-hydroxysteroid clehydrogenases (20 alpha-HSDs), sulfatase and sulfotransferase, and estrogen (ERs) and progesterone (PRs) receptors in samples of endometrial cancer and adjacent normal endometrium," scientists writing in the journal Molecular and Cellular Endocrinology report.
"No significant gene up-regulation was seen, although aromatase, AKR1C3, a 17 beta-HSD and 20 alpha-HSD, and AKR1C1, the major 20 alpha-HSD, were up-regulated in 50% of...
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Source: Drug Week (2009-05-29)
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