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Demyelinating Polyneuropathy

New demyelinating polyneuropathy study findings have been reported from University of Erlangen

Published in Drug Week, May 29th, 2009

"The inhibitory Fc-gamma receptor Fc gamma RIIB, expressed on myeloid and B cells, has a critical role in the balance of tolerance and autoimmunity, and is required for the antiinflammatory activity of intravenous Ig (IVIG) in various murine disease models. However, the function of Fc gamma RIIB and its regulation by IVIG in human autoimmune diseases are less well understood," scientists in Erlangen, Germany report.

"Chronic inflammatory demyelinating polyneuropathy (CIDP) is the most common treatable acquired chronic polyneuropathy, and IVIG is widely used as a first-line initial and maintenance treatment. We found that untreated patients with CIDP, compared with...

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