Adenoma
New adenoma research has been reported by scientists at Erasmus University
Published in Drug Week, June 5th, 2009
"Previous studies have demonstrated the expression of somatostatin receptor subtypes (mainly sst(5)) and dopamine (DA) receptor subtypes (mainly D-2) in smaller series of human corticotroph adenomas. In line with these findings, sst5 and D-2-targeting agents have already been used clinically in patients with Cushing's disease (CD) and have shown promising results in subsets of patients," scientists in Netherlands report.
"To what extent these receptor subtypes are coexpressed within individual adenomas, is not known however. The aim of the study was to investigate the (co-) expression of both sst and DA receptors in a large series of human corticotroph adenomas. We...
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Source: Drug Week (2009-06-05)
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