Pituitary Cancer
Data on pituitary cancer reported by researchers at Medical College of Georgia, Medical College
Published in Drug Week, August 7th, 2009
According to recent research from the United States, "Pituitary adenomas, which account for 15-20% of intracranial tumors, are associated with significant morbidity and mortality, due in part, to hormone hypersecretion and mass effects following increased proliferation. Radiotherapy and surgery remain frontline treatment options; however, adverse side effects and surgical limitations to treat invasive tumors necessitate the need for novel therapeutic targets."
"This study tested the efficacy of the histone deacetylase inhibitor (HDACi), suberoylanilide hydroxamic acid (SAHA) in GH3, and MMQ pituitary adenoma cells. Clinically achievable concentrations of SAHA (500 nM-4...
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Source: Drug Week (2009-08-07)
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