Published in Drug Week, October 16th, 2009
The mTOR complex regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, and transcription. The disregulation of the mTOR pathway is implicated as a contributing factor in various cancers which makes mTORC1 an attractive therapeutic target. The endoplasmic reticulum (ER) serves many general functions, including the facilitation of protein...
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