Published in Drug Week, January 1st, 2010
"CAM resistance in H. pylori is mostly due to point mutations (A2142G/C, A2143G) in the peptidyltransferase-encoding region of the 23S rRNA gene. In this study an enzymic colorimetry-based DNA chip was developed to analyse sing le-nucleotide polymorphisms of the 23S rRNA gene to determine the prevalence of mutations in CAM-related resistance...
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