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Boston University Medical Center

Researchers find high leptin levels may protect against Alzheimer's disease and dementia

Published in Drug Week, January 1st, 2010

Researchers from Boston University School of Medicine (BUSM) have found that higher leptin (a protein that controls weight and appetite) levels were associated with a lower incidence of Alzheimer's Disease (AD) and dementia. The study, which appears in the December 16th issue of the Journal of the American Medical Association, may open pathways for possible preventive and therapeutic interventions.

Dementia is increasingly recognized as a life-course illness where a variety of lifestyle choices interact with genetic, vascular and other risk factors to affect risk of disease. Given the rapid aging of developed and developing societies, it is projected that the prevalence...

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