Researchers design a tool to induce controlled suicide in human cells

When cells accumulate excessive errors in the proteins they produce, apoptosis is activated, that is to say, a cell suicide programme; however, beforehand the cells attempt to rectify the problem through a number of rescue responses. Scientists know only the general outline of the mechanisms behind cellular "stress responses", the interactions between them and the molecular components involved. Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have designed a new tool to study rescue signalling pathways and cell suicide in depth. A description of this method has been published in the last issue of the specialized Journal Nucleic Acids Research, included in the group...

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