Published in Drug Week, January 15th, 2010
To investigate E2F1's role in cancer progression, Brigitte M. Putzer, M.D., Ph.D., of the department of vectorology and experimental gene therapy at the University Rostock in Germany, and colleagues used E2F1 gene silencing in melanoma cells and in mice to compare cell growth and invasive potential and tumor growth and formation of metastatic lesions. The authors also examined...
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