Nervous System

Findings from E. O'Mara et al in nervous system reported

Published in Drug Week, June 11th, 2010

Investigators publish new data in the report 'Effect of vicriviroc on the QT/corrected QT interval and central nervous system in healthy subjects.' "Vicriviroc is a CCR5 antagonist in clinical development for the treatment of HIV-1. Two phase I studies were conducted to assess the safety of vicriviroc," investigators in the United States report.

"One study characterized the drug's potential to prolong the QT/corrected QT (QTc) interval and to induce arrhythmia. In this partially blind, parallel-group study, 200 healthy subjects aged 18 to 50 years were randomized in equal groups to the following regimens: (i) placebo for 9 days and a single dose of moxifloxacin at 400...

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Source: Drug Week (2010-06-11)

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